Formosa Pharmaceuticals Technology

Technology Overview|APNT™ nanoparticle formulation platform

What is APNT™ formulation platform?

Formosa Pharmaceutical’s proprietary APNT™ Formulation Platform operates on the principle of particle size reduction to improve dissolution and bioavailability, with lower risk of contamination.

See APNT™ Power in the Small

Benefits of formulation Features & Advantages of APNT™
Stable formulation
  • Stable and excellent dispersion properties even after long standing.
  • Manufacturing process occurs at mild temperatures and avoids use of harsh reagents, which preserves the integrity (crystal structure and purity) of the API.
  • Increased Bioavailability
  • With increased dissolution due to reduction of particle size and increase in surface area.
  • APNT™ allows better penetration enhance PK/PD data for low-solubility APIs.
  • Enhanced Safety Profile
  • Allows lower API concentrations due to increased penetration, with low contamination risk.
  • Increased IP value of asset
  • APNT™ has acquired 50 patents in multiple countries / regions to support formulation’s intellectual property strategy.
  • Lower investment in production and increased environmental sustainability
  • Reduced concentration may decrease the necessary API and manufacture scale.
  • Aseptic Filtration is possible (<200 nm), simplifying the manufacturing environment and process.
  • APNT™ Can Help Drugs With Poor Solubility or Bioavailability:

    Increasing dissolution and absorption, enhancing efficacy while decreasing side effects, and reducing unnecessary dose.
    • Increasing the success rate for new drugs
    • Exploring new possibilities on existing drugs
    • Giving an unsuccessful drug asset an alternative
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